螺内酯治疗难治性高血压的研究进展

申庆荣, 李刚

中国医院药学杂志 ›› 2016, Vol. 36 ›› Issue (23) : 2126-2130.

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中国医院药学杂志 ›› 2016, Vol. 36 ›› Issue (23) : 2126-2130. DOI: 10.13286/j.cnki.chinhosppharmacyj.2016.23.23
综述

螺内酯治疗难治性高血压的研究进展

  • 申庆荣1, 李刚2
作者信息 +

Research progress of treatment against resistant hypertension by spironolactone

  • SHEN Qing-rong1, LI Gang2
Author information +
文章历史 +

摘要

难治性高血压一直是高血压治疗的难点,通常使用多种药物治疗仍不能达标,能引起心、脑、肾等严重靶器官损害。近年来研究发现,在原治疗基础上加用螺内酯能有效促进难治性高血压的达标,故本文就螺内酯的作用机制和临床应用进行综述。

Abstract

Resistant hypertension is difficult to be cured, though many drugs have been developed. Moreover, antihypertensive drugs can cause many adverse drug reactions and damage organs such as heart, brain, kidney, etc.. In recent years, it is found that spironolactone added into basic therapeutic regimen can effectively improve therapeutic effects of resistant hypertension. Therefore, this paper summarizes mechanism and rational use of spironolactone in literatures.

关键词

螺内酯 / 难治性高血压

Key words

spironolactone / resistant hypertension

引用本文

导出引用
申庆荣, 李刚. 螺内酯治疗难治性高血压的研究进展[J]. 中国医院药学杂志, 2016, 36(23): 2126-2130 https://doi.org/10.13286/j.cnki.chinhosppharmacyj.2016.23.23
SHEN Qing-rong, LI Gang. Research progress of treatment against resistant hypertension by spironolactone[J]. Chinese Journal of Hospital Pharmacy, 2016, 36(23): 2126-2130 https://doi.org/10.13286/j.cnki.chinhosppharmacyj.2016.23.23
中图分类号: R983+.1   

参考文献

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